Novel thiosemicarbazide-oxadiazole hybrids as unprecedented inhibitors of yeast α-glucosidase and in silico binding analysis
Compounds 1-18, new oxadiazole-thiosemicarbazide hybrids, were synthesized using a five-step reaction sequence in excellent yields. All the synthesized analogs exhibited exceptional α-glucosidase inhibitory potentials in the range of 0.4-38.1 μM. Among the current series, it was observed that the fl...
| Published in: | RSC Advances |
|---|---|
| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
Royal Society of Chemistry
2016
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84964523904&doi=10.1039%2fc5ra28012e&partnerID=40&md5=aa6dbb8465ae9ee063c8c7663e2f2783 |