Coupling genotyping and computational modeling in prediction of antiepileptic drugs that cause Stevens Johnson syndrome and toxic epidermal Necrolysis for carrier of HLA-B*15:02
Purpose. The importance of HLA-B*15:02 genotyping to avoid carbamazepine induced SJS/TEN and molecular modeling to predict the role of HLA-B*15:0 and AEDs induced SJS/TEN are investigated. Methods. DNA was extracted from eighty-six patients. The patients were genotyped by AS-PCR. Computational model...
| Published in: | Journal of Pharmacy and Pharmaceutical Sciences |
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| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
Canadian Society for Pharmaceutical Sciences
2016
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84961762798&doi=10.18433%2fJ38G7X&partnerID=40&md5=0aa9ba3460c8df8691191864ad1bf729 |