Synthesis, in vitro and Docking Studies of New Flavone Ethers as α-Glucosidase Inhibitors

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Synthesis, in vitro and Docking Studies of New Flavone Ethers as α-Glucosidase Inhibitors

We report herein the synthesis, α-glucosidase inhibition and docking studies for a series of 3-15 new flavones. A simple nucleophilic substitution reaction takes place between 3′hydroxyflavone (2) with halides to afford the new flavones. Chalcone (1), 3′hydroxyflavone (2) and the newly synthesized f...

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Bibliographic Details
Published in:	Chemical Biology and Drug Design
Main Author:	Imran S.; Taha M.; Ismail N.H.; Kashif S.M.; Rahim F.; Jamil W.; Wahab H.; Khan K.M.
Format:	Article
Language:	English
Published:	Blackwell Publishing Ltd 2016
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-84960398049&doi=10.1111%2fcbdd.12666&partnerID=40&md5=ebe013f631694ad2e66f20fc7a1ebfde

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