Synthesis, in vitro and Docking Studies of New Flavone Ethers as α-Glucosidase Inhibitors
We report herein the synthesis, α-glucosidase inhibition and docking studies for a series of 3-15 new flavones. A simple nucleophilic substitution reaction takes place between 3′hydroxyflavone (2) with halides to afford the new flavones. Chalcone (1), 3′hydroxyflavone (2) and the newly synthesized f...
| Published in: | Chemical Biology and Drug Design |
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| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
Blackwell Publishing Ltd
2016
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84960398049&doi=10.1111%2fcbdd.12666&partnerID=40&md5=ebe013f631694ad2e66f20fc7a1ebfde |