CYP2D6 Genetic Polymorphisms and Phenotypes in Different Ethnicities of Malaysian Breast Cancer Patients
The cytochrome P450, family 2, subfamily D, polypeptide 6 (CYP2D6) is an enzyme that is predominantly involved in the metabolism of tamoxifen. Genetic polymorphisms of the CYP2D6 gene may contribute to inter-individual variability in tamoxifen metabolism, which leads to the differences in clinical r...
Published in: | Breast Journal |
---|---|
Main Author: | Chin F.W.; Chan S.C.; Abdul Rahman S.; Noor Akmal S.; Rosli R. |
Format: | Article |
Language: | English |
Published: |
Blackwell Publishing Inc.
2016
|
Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84956774811&doi=10.1111%2ftbj.12518&partnerID=40&md5=e7a1b9d6e3bbd5dbcd957a173571b3e2 |
Similar Items
-
The risk of recurrence in breast cancer patients treated with tamoxifen: Polymorphisms of CYP2D6 and ABCB1
by: Teh L.K.; Mohamed N.I.; Salleh M.Z.; Rohaizak M.; Shahrun N.S.; Saladina J.J.; Shia J.K.S.; Roslan H.; Sood S.; Rajoo T.S.; Muniandy S.P.; Henry G.; Ngow H.A.; Hla U K.T.; Din J.
Published: (2012) -
The relevance of CYP2D6 genetic polymorphism on chronic metoprolol therapy in cardiovascular patients
by: Ismail R.; Teh L.K.
Published: (2006) -
Genetic polymorphism of CYP2C8 in three Malaysian ethnics: CYP2C8*2 and CYP2C8*3 are found in Malaysian Indians
by: Muthiah Y.D.; Lee W.L.; Teh L.K.; Ong C.E.; Ismail R.
Published: (2005) -
Inference of the Genetic Polymorphisms of CYP2D6 in Six Subtribes of the Malaysian Orang Asli from Whole-Genome Sequencing Data
by: Yu C.Y.; Ang G.Y.; Subramaniam V.; Johari James R.; Ahmad A.; Abdul Rahman T.; Mohd Nor F.; Shaari S.A.; Teh L.K.; Salleh M.Z.
Published: (2017) -
Malaysian Indians are genetically similar to Caucasians: CYP2C9 polymorphism
by: Zainuddin Z.; Teh L.K.; Suhaimi A.W.M.; Ismail R.
Published: (2006)