CYP2D6 Genetic Polymorphisms and Phenotypes in Different Ethnicities of Malaysian Breast Cancer Patients

The cytochrome P450, family 2, subfamily D, polypeptide 6 (CYP2D6) is an enzyme that is predominantly involved in the metabolism of tamoxifen. Genetic polymorphisms of the CYP2D6 gene may contribute to inter-individual variability in tamoxifen metabolism, which leads to the differences in clinical r...

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Bibliographic Details
Published in:Breast Journal
Main Author: Chin F.W.; Chan S.C.; Abdul Rahman S.; Noor Akmal S.; Rosli R.
Format: Article
Language:English
Published: Blackwell Publishing Inc. 2016
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-84956774811&doi=10.1111%2ftbj.12518&partnerID=40&md5=e7a1b9d6e3bbd5dbcd957a173571b3e2