Synthesis of novel inhibitors of β-glucuronidase based on the benzothiazole skeleton and their molecular docking studies

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Synthesis of novel inhibitors of β-glucuronidase based on the benzothiazole skeleton and their molecular docking studies

A series of benzothiazole based oxadiazole analogs 1-20 was synthesized by reacting intermediate sulfite adducts with 2-aminothiophenol and refluxing in DMF for 12 h to afford ester analog I which, on further refluxing in methanolic hydrazine hydrate solution, afforded compound II. Compound II was t...

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Bibliographic Details
Published in:	RSC Advances
Main Author:	Taha M.; Ismail N.H.; Imran S.; Selvaraj M.; Rahim F.
Format:	Article
Language:	English
Published:	Royal Society of Chemistry 2016
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-84953923975&doi=10.1039%2fc5ra23072a&partnerID=40&md5=57f7d191e961c2f3fc5764f5bf504ec7

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