Synthesis of novel inhibitors of β-glucuronidase based on the benzothiazole skeleton and their molecular docking studies
A series of benzothiazole based oxadiazole analogs 1-20 was synthesized by reacting intermediate sulfite adducts with 2-aminothiophenol and refluxing in DMF for 12 h to afford ester analog I which, on further refluxing in methanolic hydrazine hydrate solution, afforded compound II. Compound II was t...
| Published in: | RSC Advances |
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| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
Royal Society of Chemistry
2016
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84953923975&doi=10.1039%2fc5ra23072a&partnerID=40&md5=57f7d191e961c2f3fc5764f5bf504ec7 |