2-(2'-pyridyl) benzimidazole analogs and their ß-glucuronidase inhibitory activity
Synthesis of 2-(2'-pyridyl) benzimidazole analogs 1-11 have been carried out and evaluated for in vitro ß-glucuronidase inhibitory potential. The compounds 4 (IC50 = 4.06 ± 0.34 μM), 5 (IC50 = 09.63 ± 0.81 μM), 1 (IC50 = 19.66 ± 0.44 μM), 7 (IC50 = 24.75 ± 0.25 μM), 6 (IC50 = 26.30 ± 1.37 μM),...
| Published in: | Journal of the Chemical Society of Pakistan |
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| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
Chemical Society of Pakistan
2015
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84953331043&partnerID=40&md5=a41f6149582721818f824995a58265a8 |