Benzimidazole derivatives as new α-glucosidase inhibitors and in silico studies
Newly synthesized benzimidazole hydrazone derivatives 1-26 were evaluated for their α-glucosidase inhibitory activity. Compounds 1-26 exhibited varying degrees of yeast α-glucosidase inhibitory activity with IC50 values between 8.40 ± 0.76 and 179.71 ± 1.11 μM when compared with standard acarbose. I...
| Published in: | Bioorganic Chemistry |
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| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
Academic Press Inc.
2016
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84948649641&doi=10.1016%2fj.bioorg.2015.11.006&partnerID=40&md5=93ec464c2d71e54bbd8588cac5d567e0 |