Heparins in ulcerative colitis: Proposed mechanisms of action and potential reasons for inconsistent clinical outcomes

QR Code

Heparins in ulcerative colitis: Proposed mechanisms of action and potential reasons for inconsistent clinical outcomes

Current drug therapies for ulcerative colitis (UC) are not completely effective in managing moderate-to-severe UC and approximately 20% of patients with severe UC require surgical interventions. Heparins, polydisperse mixtures of non-anticoagulant and anticoagulant oligosaccharides, are widely used...

Full description

Bibliographic Details
Published in:	Expert Review of Clinical Pharmacology
Main Author:	Lean Q.Y.; Gueven N.; Eri R.D.; Bhatia R.; Sohal S.S.; Stewart N.; Peterson G.M.; Patel R.P.
Format:	Review
Language:	English
Published:	Taylor and Francis Ltd 2015
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-84946493086&doi=10.1586%2f17512433.2015.1082425&partnerID=40&md5=e14a3a970bafd6fcf42897797fb0eb61

Similar Items

Orally Administered Enoxaparin Ameliorates Acute Colitis by Reducing Macrophage-Associated Inflammatory Responses
by: Lean Q.Y.; Eri R.D.; Randall-Demllo S.; Sohal S.S.; Stewart N.; Peterson G.M.; Gueven N.; Patel R.P.
Published: (2015)

Therapeutic potential of enoxaparin in lichen planus: Exploring reasons for inconsistent reports
by: Patel R.P.; Shastri M.D.; Ming L.C.; Zaidi S.R.; Peterson G.M.
Published: (2018)

Fucoidan extracts ameliorate acute colitis
by: Lean Q.Y.; Eri R.D.; Fitton J.H.; Patel R.P.; Gueven N.
Published: (2015)

A case of urgent colonoscopic hemostasis of a cecal hemorrhagic ulceration in a patient receiving heparin for COVID-19 coagulopathy
by: Yoshida N.; Hirose R.; Watanabe M.; Yamazaki M.; Hashimoto S.; Matsubara S.; Kasamatsu Y.; Fujita N.; Rani R.A.; Dohi O.; Inoue K.; Naito Y.; Itoh Y.
Published: (2021)

Natural and synthetic polymer-based smart biomaterials for management of ulcerative colitis: a review of recent developments and future prospects
by: Sohail M.; Mudassir; Minhas M.U.; Khan S.; Hussain Z.; de Matas M.; Shah S.A.; Khan S.; Kousar M.; Ullah K.
Published: (2019)

Interplay of the quality of ciprofloxacin and antibiotic resistance in developing countries
by: Sharma D.; Patel R.P.; Zaidi S.T.R.; Sarker M.M.R.; Lean Q.Y.; Ming L.C.
Published: (2017)

Reasons behind providing care for older persons
by: Dahlan A.; Dzaki N.M.; Adeli I.S.; Nurhidayah N.
Published: (2024)

Amoebic colitis mimicking a colonic carcinoma
by: Abdul Rani R.; Limun M.F.; Naidu J.; Ngiu C.S.; Raja Ali R.A.
Published: (2016)

Identifying Scientific Reasoning Skills of Science Education Students
by: Zulkipli Z.A.; Mohd Yusof M.M.; Ibrahim N.; Dalim S.F.
Published: (2020)

Content analysis of mobile health applications on diabetes mellitus
by: Izahar S.; Lean Q.Y.; Hameed M.A.; Murugiah M.K.; Patel R.P.; Al-Worafi Y.M.; Wong T.W.; Ming L.C.
Published: (2017)

Clinical reasoning training sessions for health educators—A scoping review
by: Mohd Tambeh S.N.; Yaman M.N.
Published: (2023)

INCONSISTENCY OF AIR QUALITY LEVEL DURING SEVERAL PHASES OF COVID-19 MOVEMENT RESTRICTIONS IN MALAYSIA
by: ABDULLAH S.; ROZALI N.H.S.C.; MANSOR A.A.; AHMAD A.N.; AHMED A.N.; DOM N.C.; ZULKIFLI M.F.R.; JUSOH S.M.; MANSOR W.N.W.; ISMAIL M.
Published: (2023)

Heparin Epitope Imprinted Via Sol-Gel Process on Silica Surface: Effect of Template: Monomer Ratio Studies
by: Nasir A.M.; Ishak N.; Anuar A.; Abdullah S.
Published: (2023)

Methanol extract of bauhinia purpurea leaf possesses anti-ulcer activity
by: Zakaria Z.A.; Abdul Hisam E.E.; Norhafizah M.; Rofiee M.S.; Othman F.; Hasiah A.H.; Vasudevan M.
Published: (2012)

A 5-year clinicopathological study on microscopic colitis at a Malaysian tertiary hospital
by: Hafidz M.I.A.; Zulkifli K.K.; Win T.T.; Zin A.A.M.; Mustaffa N.
Published: (2021)

Investigating Reasons for the Unsuccessful Extension of Time (EoT) Claim in the Malaysian Construction Industry; Views from the Professionals
by: Yusuwan N.M.; Adnan H.; Mahat N.A.A.; Ahmad Z.Z.; Baharuddin H.E.A.
Published: (2022)

Cross-border Collaboration to Improve Access to Medicine: Association of Southeast Asian nations perspective
by: Lee K.S.; Ming L.C.; Lean Q.Y.; Yee S.M.; Patel R.; Taha N.A.; Kassab Y.W.
Published: (2019)

N95 respirator associated pressure ulcer amongst COVID-19 health care workers
by: Lam U.-N.; Md. Mydin Siddik N.S.F.; Mohd Yussof S.J.; Ibrahim S.
Published: (2020)

Proposed Nutritional Guideline for Motorcycling Activities
by: Yong T.H.; Yong Y.M.R.; Ma’arof M.I.N.; Shavarebi K.; Raman J.; See J.; Husain H.; Ghani A.R.A.; Chala G.T.; Nasir M.F.M.
Published: (2024)

A descriptive study on the knowledge and attitude of nurses toward the prevention of pressure ulcers in the intensive care unit
by: Abdullah S.S.S.; Bakar N.; Shohor N.A.
Published: (2024)

Immunophenotyping of Gastritis, Gastric Ulcer and Gastric Cancer using a Cluster of Differentiation (CD) Antibody Microarray
by: Hanafiah A.; Sukri A.; Kosai N.R.; Shuhaili M.A.; Taher M.M.; Ali R.A.R.
Published: (2023)

Recent advances in polymer-based wound dressings for the treatment of diabetic foot ulcer: An overview of state-of-the-art
by: Hussain Z.; Thu H.E.; Shuid A.N.; Katas H.; Hussain F.
Published: (2018)

The proposed framework and challenges towards smart city implementation
by: Rahman W.F.W.A.; Abdalla A.H.; Islam M.R.
Published: (2021)

Proposed improvements to Istibdal implementation management in the state of Penang
by: Mohammed Noor A.; Asni F.; Hasbulah M.H.; Ramle M.R.
Published: (2024)

In Vivo Antioxidant and Antiulcer Activity of Parkia speciosa Ethanolic Leaf Extract against Ethanol-Induced Gastric Ulcer in Rats
by: Al Batran R.; Al-Bayaty F.; Jamil Al-Obaidi M.M.; Abdualkader A.M.; Hadi H.A.; Ali H.M.; Abdulla M.A.
Published: (2013)

A narrative action on the battle against hunger using mushroom, peanut, and soybean-based wastes
by: Mohd Zaini N.A.; Azizan N.A.Z.; Abd Rahim M.H.; Jamaludin A.A.; Raposo A.; Raseetha S.; Zandonadi R.P.; BinMowyna M.N.; Raheem D.; Lho L.H.; Han H.; Wan-Mohtar W.A.A.Q.I.
Published: (2023)

Towards Precision Health in Weight Reduction: Thematic Content Analysis of an Open-Ended Survey on Reasons Why Morbidly Obese Patients Want to Lose Weight
by: Md-Yasin M.; Ismail I.A.; Malek K.A.; Yusoff K.; Bulgiba A.
Published: (2022)

A proposed model of motivational influences on academic achievement with flow as the mediator
by: Mustafa S.M.S.; Elias H.; Noah S.M.; Roslan S.
Published: (2010)

Piano Teaching Action Recognition Based on LSTM
by: Sha R.; Tan B.
Published: (2024)

A proposed aerobic granules size development scheme for aerobic granulation process
by: Dahalan F.A.; Abdullah N.; Yuzir A.; Olsson G.; Salmiati; Hamdzah M.; Din M.F.M.; Ahmad S.A.; Khalil K.A.; Anuar A.N.; Noor Z.Z.; Ujang Z.
Published: (2015)

The Linguistic and Grammatical Foundations for Understanding Prophetic Hadith Texts: Proposed Strategies and Mechanisms
by: Othman, et al.
Published: (2024)

Smart Data for Sustainable Halal Supply Chain in Kuala Lumpur: A Proposal
by: Nizar N.N.A.; Abidin S.A.S.Z.; Taib M.N.
Published: (2023)

A proposed model in fundamental of decision making process at local government level
by: Ngah K.; Zakaria Z.; Hussin Z.H.; Noordin N.; Mustaffa J.; Zool M.; Mohamed Sawal M.Z.H.
Published: (2012)

Private Tahfiz institution governance: A proposed transformation via social entrepreneruship model
by: Anas N.; Samori Z.; Hamid M.Y.; Zulkipli S.N.; Noor M.S.M.
Published: (2019)

Male oxidative stress infertility (MOSI): Proposed terminology and clinical practice guidelines for management of idiopathic male infertility
by: Agarwal A.; Parekh N.; Selvam M.K.P.; Henkel R.; Shah R.; Homa S.T.; Ramasamy R.; Ko E.; Tremellen K.; Esteves S.; Majzoub A.; Alvarez J.G.; Gardner D.K.; Jayasena C.N.; Ramsay J.W.; Cho C.-L.; Saleh R.; Sakkas D.; Hotaling J.M.; Lundy S.D.; Vij S.; Marmar J.; Gosalvez J.; Sabanegh E.; Park H.J.; Zini A.; Kavoussi P.; Micic S.; Smith R.; Busetto G.M.; Bakircioǧlu M.E.; Haidl G.; Balercia G.; Puchalt N.G.; Ben-Khalifa M.; Tadros N.; Kirkman-Browne J.; Moskovtsev S.; Huang X.; Borges E., et al.
Published: (2019)

Navigating the future of industry 4.0 in Malaysia: A proposed conceptual framework on SMEs’ readiness
by: Muhamad M.Q.B.; Mohamad S.J.A.N.S.; Nor N.M.
Published: (2021)

Mechanical Properties of Epoxy-UHMWPE Variant for Hip Implant Proposal: Preliminary Study on Numerical and Experimental
by: Manap M.F.A.; Shuib S.; Romli A.Z.; Ahmad F.N.; Md Noh N.S.S.; Zainudin M.
Published: (2024)

Exploring Theories for Enhancing School Children's Path to Success as Entrepreneurs: A proposed systematic review
by: Aziz, et al.
Published: (2024)

THE RESOLUTION OF QUADRATIC INEQUALITY PROBLEMS IN MATHEMATICS: DISCREPANCIES BETWEEN THOUGHT AND ACTION
by: Faradiba S.S.; Alifiani; Md Nasir N.A.
Published: (2024)

Grammatical Evolution based Controller Design for Vehicle Robot Action Learning
by: Sukarman, et al.
Published: (2023)