Heparins in ulcerative colitis: Proposed mechanisms of action and potential reasons for inconsistent clinical outcomes

Current drug therapies for ulcerative colitis (UC) are not completely effective in managing moderate-to-severe UC and approximately 20% of patients with severe UC require surgical interventions. Heparins, polydisperse mixtures of non-anticoagulant and anticoagulant oligosaccharides, are widely used...

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Bibliographic Details
Published in:Expert Review of Clinical Pharmacology
Main Author: Lean Q.Y.; Gueven N.; Eri R.D.; Bhatia R.; Sohal S.S.; Stewart N.; Peterson G.M.; Patel R.P.
Format: Review
Language:English
Published: Taylor and Francis Ltd 2015
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-84946493086&doi=10.1586%2f17512433.2015.1082425&partnerID=40&md5=e14a3a970bafd6fcf42897797fb0eb61