Synthesis of potent urease inhibitors based on disulfide scaffold and their molecular docking studies
Disulfide analogs (1-20) have been synthesized, characterized by HR-MS,1H NMR and13C NMR and screened for urease inhibitory potential. All compounds were found to have varied degree of urease inhibitory potential ranging in between 0.4 ± 0.01 and 18.60 ± 1.24 μM when compared with standard inhibitor...
| Published in: | Bioorganic and Medicinal Chemistry |
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| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
Elsevier Ltd
2015
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84946228073&doi=10.1016%2fj.bmc.2015.10.017&partnerID=40&md5=e220546463e982308f98d0ae9ede33ff |