Synthesis of 4-thiazolidinone analogs as potent in vitro anti-urease agents
4-Thiazolidinone analogs 1-20 were synthesized, characterized by 1H NMR and EI-MS and investigated for urease inhibitory activity. All twenty (20) analogs exhibited varied degree of urease inhibitory potential with IC50 values 1.73-69.65 μM, if compared with standard thiourea having IC50 value of 21...
Published in: | Bioorganic Chemistry |
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Main Author: | |
Format: | Article |
Language: | English |
Published: |
Academic Press Inc.
2015
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Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84945937324&doi=10.1016%2fj.bioorg.2015.10.005&partnerID=40&md5=cfe737f28b6a3625c62dfe6020251128 |