Synthesis of novel flavone hydrazones: In-vitro evaluation of α-glucosidase inhibition, QSAR analysis and docking studies

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Synthesis of novel flavone hydrazones: In-vitro evaluation of α-glucosidase inhibition, QSAR analysis and docking studies

Thirty derivatives of flavone hydrazone (5e34) had been synthesized through a five-step reaction and screened for their a-glucosidase inhibition activity. Chalcone 1 was synthesized through aldol condensation then subjected through oxidative cyclization, esterification, and condensation reaction to...

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Bibliographic Details
Published in:	European Journal of Medicinal Chemistry
Main Author:	Imran S.; Taha M.; Ismail N.H.; Kashif S.M.; Rahim F.; Jamil W.; Hariono M.; Yusuf M.; Wahab H.
Format:	Article
Language:	English
Published:	Elsevier Masson SAS 2015
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-84944728488&doi=10.1016%2fj.ejmech.2015.10.017&partnerID=40&md5=99b7cccaf3d9062f18583dd5b1672e64

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