Synthesis of novel flavone hydrazones: In-vitro evaluation of α-glucosidase inhibition, QSAR analysis and docking studies
Thirty derivatives of flavone hydrazone (5e34) had been synthesized through a five-step reaction and screened for their a-glucosidase inhibition activity. Chalcone 1 was synthesized through aldol condensation then subjected through oxidative cyclization, esterification, and condensation reaction to...
| Published in: | European Journal of Medicinal Chemistry |
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| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
Elsevier Masson SAS
2015
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84944728488&doi=10.1016%2fj.ejmech.2015.10.017&partnerID=40&md5=99b7cccaf3d9062f18583dd5b1672e64 |