The implication of the polymorphisms of COX-1, UGT1A6, and CYP2C9 among cardiovascular disease patients treated with aspirin

The implication of the polymorphisms of COX-1, UGT1A6, and CYP2C9 among cardiovascular disease patients treated with aspirin

Purpose. Enzymes potentially responsible for the pharmacokinetic variations of aspirin include cyclooxygenase-1 (COX-1), UDP-glucuronosyltransferase (UGT1A6) and P450 (CYP) (CYP2C9). We therefore aimed to determine the types and frequencies of variants of COX-1 (A-842G), UGT1A6 (UGT1A6*2; A541G and...

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Bibliographic Details
Published in:Journal of Pharmacy and Pharmaceutical Sciences
Main Author: Abdul Jalil N.J.; Bannur Z.; Derahman A.; Maskon O.; Darinah N.; Hamidi H.; Ali O.; Gunasekaran; Rafizi M.; Azreen N.I.; Kek T.L.; Salleh M.Z.
Format: Article
Language:English
Published: Canadian Society for Pharmaceutical Sciences 2015
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-84943415180&doi=10.18433%2fj3fc7f&partnerID=40&md5=88bb2ade15b98afa66714457fcef2385

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