Aloe emodin induces apoptosis in ER+-breast cancer cells; MCF-7 through IGF-1R signalling pathway

Two-third of breast cancer patients expressed estrogen receptors (ER)s and received endocrine treatment with established anti-estrogens such as tamoxifen. But the action and acquired resistance during treatment are largely unknown. In contrary, phytochemicals are more selective and less cytotoxic to...

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Bibliographic Details
Published in:Sains Malaysiana
Main Author: Amin I.M.; Kamaludin R.; Yeap S.K.; Isa M.R.; Mohd Rosdy N.M.M.N.; Siran R.; Kadir S.H.S.A.; Hasani N.A.H.
Format: Article
Language:English
Published: Penerbit Universiti Kebangsaan Malaysia 2015
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-84942020241&doi=10.17576%2fjsm-2015-4408-09&partnerID=40&md5=95a3dcdbf825c439e17dfebdb74619dc