Novel 2,5-disubtituted-1,3,4-oxadiazoles with benzimidazole backbone: A new class of β-glucuronidase inhibitors and in silico studies
Abstract A library of novel 2,5-disubtituted-1,3,4-oxadiazoles with benzimidazole backbone (3a-3r) was synthesized and evaluated for their potential as β-glucuronidase inhibitors. Several compounds such as 3a-3d, 3e-3j, 3l-3o, 3q and 3r showed excellent inhibitory potentials much better than the sta...
| Published in: | Bioorganic and Medicinal Chemistry |
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| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
Elsevier Ltd
2015
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84937437445&doi=10.1016%2fj.bmc.2015.04.081&partnerID=40&md5=9b76ed8fe1d93152c79a084d6a809102 |