Synthesis crystal structure of 2-methoxybenzoylhydrazones and evaluation of their α-glucosidase and urease inhibition potential
Compounds 1-30 showed varying degree of α-glucosidase inhibition with IC50 values ranging between 187 and 420 μM. Compounds 1, 2, 3, 6, 8, 12, and 4 (IC50 = 187.7 ± 3.05, 203.4 ± 4.0, 240.7 ± 1.9, 252.9 ± 3.9, 285.2 ± 6.3, 399.07 ± 1.2, and 420.36 ± 5.6 μM, respectively) were found to be more active...
| Published in: | Medicinal Chemistry Research |
|---|---|
| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
Birkhauser Boston
2015
|
| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84934852218&doi=10.1007%2fs00044-014-1213-8&partnerID=40&md5=f9766e8be167226cebc66a658178de74 |