Synthesis of novel derivatives of oxindole, their urease inhibition and molecular docking studies

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Synthesis of novel derivatives of oxindole, their urease inhibition and molecular docking studies

Abstract We synthesized a series of novel 5-24 derivatives of oxindole. The synthesis started from 5-chlorooxindole, which was condensed with methyl 4-carboxybezoate and result in the formation of benzolyester derivatives of oxindole which was then treated with hydrazine hydrate. The oxindole benzoy...

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Bibliographic Details
Published in:	Bioorganic and Medicinal Chemistry Letters
Main Author:	Taha M.; Ismail N.H.; Khan A.; Shah S.A.A.; Anwar A.; Halim S.A.; Fatmi M.Q.; Imran S.; Rahim F.; Khan K.M.
Format:	Article
Language:	English
Published:	Elsevier Ltd 2015
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-84934830620&doi=10.1016%2fj.bmcl.2015.05.069&partnerID=40&md5=72aca8fc8274040351c1a7dab5aa9a93

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