Synthesis of novel derivatives of oxindole, their urease inhibition and molecular docking studies

Abstract We synthesized a series of novel 5-24 derivatives of oxindole. The synthesis started from 5-chlorooxindole, which was condensed with methyl 4-carboxybezoate and result in the formation of benzolyester derivatives of oxindole which was then treated with hydrazine hydrate. The oxindole benzoy...

Full description

Bibliographic Details
Published in:Bioorganic and Medicinal Chemistry Letters
Main Author: Taha M.; Ismail N.H.; Khan A.; Shah S.A.A.; Anwar A.; Halim S.A.; Fatmi M.Q.; Imran S.; Rahim F.; Khan K.M.
Format: Article
Language:English
Published: Elsevier Ltd 2015
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-84934830620&doi=10.1016%2fj.bmcl.2015.05.069&partnerID=40&md5=72aca8fc8274040351c1a7dab5aa9a93