Synthesis and biological evaluation of novel phenanthridinyl piperazine triazoles via click chemistry as anti-proliferative agents

The preliminary results describe synthesis of a series of novel 6-(4-((substituted-1H-1,2,3-triazol-4-yl)methyl)piperazin-1-yl)phenanthridine analogs using hybrid approach employing copper(I)-catalyzed azide-alkyne cycloaddition and their evaluation as antiproliferative agents against four cancer ce...

Full description

Bibliographic Details
Published in:Medicinal Chemistry Research
Main Author: Nagesh H.N.; Suresh N.; Prakash G.V.S.B.; Gupta S.; Rao J.V.; Sekhar K.V.G.C.
Format: Article
Language:English
Published: Birkhauser Boston 2015
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-84926482705&doi=10.1007%2fs00044-014-1142-6&partnerID=40&md5=d57036eae9a7303722f809c4acfe5526