Inhibition of prostaglandin E2 production by synthetic minor prenylated chalcones and flavonoids: Synthesis, biological activity, crystal structure, and in silico evaluation

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Inhibition of prostaglandin E2 production by synthetic minor prenylated chalcones and flavonoids: Synthesis, biological activity, crystal structure, and in silico evaluation

The discovery of potent inhibitors of prostaglandin E2 (PGE 2) synthesis in recent years has been proven to be an important game changer in pharmaceutical industry. It is known that excessive production of PGE2 triggers a vast array of biological signals and physiological events that contributes to...

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Bibliographic Details
Published in:	Bioorganic and Medicinal Chemistry Letters
Main Author:	Rullah K.; Mohd Aluwi M.F.F.; Yamin B.M.; Abdul Bahari M.N.; Wei L.S.; Ahmad S.; Abas F.; Ismail N.H.; Jantan I.; Wai L.K.
Format:	Article
Language:	English
Published:	Elsevier Ltd 2014
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-84905899348&doi=10.1016%2fj.bmcl.2014.06.061&partnerID=40&md5=621287f1c20ac7c89bdc516f2f4e8182

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