Inhibition of prostaglandin E2 production by synthetic minor prenylated chalcones and flavonoids: Synthesis, biological activity, crystal structure, and in silico evaluation
The discovery of potent inhibitors of prostaglandin E2 (PGE 2) synthesis in recent years has been proven to be an important game changer in pharmaceutical industry. It is known that excessive production of PGE2 triggers a vast array of biological signals and physiological events that contributes to...
| Published in: | Bioorganic and Medicinal Chemistry Letters |
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| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
Elsevier Ltd
2014
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84905899348&doi=10.1016%2fj.bmcl.2014.06.061&partnerID=40&md5=621287f1c20ac7c89bdc516f2f4e8182 |