Synthesis of novel derivatives of 4-methylbenzimidazole and evaluation of their biological activities

4-Methylbenzimidazole 1-28 novel derivatives were synthesized and evaluated for their antiglycation and antioxidant activities. Compounds 1-7 and 11 showed excellent activities ranged 140-280 μM, better than standard drug rutin (294.46 ± 1.50 μM). Compound 1-28 were also evaluated for DPPH activitie...

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Bibliographic Details
Published in:European Journal of Medicinal Chemistry
Main Author: Taha M.; Ismail N.H.; Jamil W.; Rashwan H.; Kashif S.M.; Sain A.A.; Adenan M.I.; Anouar E.H.; Ali M.; Rahim F.; Khan K.M.
Format: Article
Language:English
Published: Elsevier Masson SAS 2014
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-84905161829&doi=10.1016%2fj.ejmech.2014.07.078&partnerID=40&md5=bf97c4e0f2f2d9107b8b4ff76f9ebc45