Synthesis and β-glucuronidase inhibitory activity of 2-arylquinazolin-4(3H)-ones
2-Arylquinazolin-4(3H)-ones 1-25 were synthesized by reacting anthranilamide with various benzaldehydes using CuCl2·2H 2O as a catalyst in ethanol under reflux. Synthetic 2-arylquinazolin-4(3H)-ones 1-25 were evaluated for their β-glucuronidase inhibitory potential. A trend of inhibition IC50 agains...
| Published in: | Bioorganic and Medicinal Chemistry |
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| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
Elsevier Ltd
2014
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84901927895&doi=10.1016%2fj.bmc.2014.04.039&partnerID=40&md5=0e2ea5b060a41cd08faa053639f44ecd |