Synthesis and molecular docking studies of potent α-glucosidase inhibitors based on biscoumarin skeleton
In our effort directed toward the discovery of new anti-diabetic agent for the treatment of diabetes, a library of biscoumarin derivative 1-18 was synthesized and evaluated for α-glucosidase inhibitory potential. All eighteen (18) compounds displayed assorted α-glucosidase activity with IC50 values...
| Published in: | European Journal of Medicinal Chemistry |
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| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
Elsevier Masson SAS
2014
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84901047505&doi=10.1016%2fj.ejmech.2014.05.010&partnerID=40&md5=f812216d7ea4978dcf86e9b7983709e8 |