Pharmacogenotyping of CYP3A5 in predicting dose-adjusted trough levels of tacrolimus among Malaysian kidney-transplant patients
Tacrolimus (FK506) is a calcineurin inhibitor with a narrow therapeutic index that exhibits large interindividual variation. Seventy-eight kidney transplant patients treated with tacrolimus were recruited to study the correlation of dose adjusted trough level (level/dose; L/D) of tacrolimus with CYP...
Published in: | Canadian Journal of Physiology and Pharmacology |
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Main Author: | |
Format: | Article |
Language: | English |
Published: |
2014
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Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84891554610&doi=10.1139%2fcjpp-2013-0128&partnerID=40&md5=cbac989970de0b3edee394ad8f1a606c |