Pharmacogenotyping of CYP3A5 in predicting dose-adjusted trough levels of tacrolimus among Malaysian kidney-transplant patients

Tacrolimus (FK506) is a calcineurin inhibitor with a narrow therapeutic index that exhibits large interindividual variation. Seventy-eight kidney transplant patients treated with tacrolimus were recruited to study the correlation of dose adjusted trough level (level/dose; L/D) of tacrolimus with CYP...

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Bibliographic Details
Published in:Canadian Journal of Physiology and Pharmacology
Main Author: Hamzah S.; Teh L.K.; Siew J.S.K.; Ahmad G.; Wong H.S.; Zakaria Z.A.; Salleh M.Z.
Format: Article
Language:English
Published: 2014
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-84891554610&doi=10.1139%2fcjpp-2013-0128&partnerID=40&md5=cbac989970de0b3edee394ad8f1a606c