Styryl-lactone goniothalamin inhibits TNF-α-induced NF-κB activation

(R)-(+)-Goniothalamin (GTN), a styryl-lactone isolated from the medicinal plant Goniothalamus macrophyllus, exhibits pharmacological activities including cytotoxic and anti-inflammatory effects. In this study, GTN modulated TNF-α induced NF-κB activation. GTN concentrations up to 20. μM showed low c...

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Bibliographic Details
Published in:Food and Chemical Toxicology
Main Author: Orlikova B.; Schumacher M.; Juncker T.; Yan C.C.; Inayat-Hussain S.H.; Hajjouli S.; Cerella C.; Dicato M.; Diederich M.
Format: Article
Language:English
Published: 2013
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-84881002603&doi=10.1016%2fj.fct.2013.06.051&partnerID=40&md5=408f7fdb3f6bb47a312fdc6bc5858ec2