Xanthine oxidase inhibition by 5-aryledene N,N'-dimethylbarbituric acid derivatives

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Xanthine oxidase inhibition by 5-aryledene N,N'-dimethylbarbituric acid derivatives

N,N'-dimethylbarbituric acid derivatives 1-24 were evaluated for their xanthine oxidase (XO) inhibitory activity. Majority of these compounds showed a good to moderate in vitro xanthine oxidase inhibitory activity (IC50 = 20.97 ± 0.29 - 327.0 ± 3.50 μM), while eight compounds were found to be c...

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Bibliographic Details
Published in:	Journal of the Chemical Society of Pakistan
Main Author:	Khan K.M.; Khan M.; Karim A.; Taha M.; Ambreen N.; Gojayev A.; Perveen S.; Choudhary M.I.
Format:	Article
Language:	English
Published:	2013
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-84878442900&partnerID=40&md5=bd50d12cd8fdab702c37c4bed5b59c8f

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