Xanthine oxidase inhibition by 5-aryledene N,N'-dimethylbarbituric acid derivatives
N,N'-dimethylbarbituric acid derivatives 1-24 were evaluated for their xanthine oxidase (XO) inhibitory activity. Majority of these compounds showed a good to moderate in vitro xanthine oxidase inhibitory activity (IC50 = 20.97 ± 0.29 - 327.0 ± 3.50 μM), while eight compounds were found to be c...
| Published in: | Journal of the Chemical Society of Pakistan |
|---|---|
| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
2013
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84878442900&partnerID=40&md5=bd50d12cd8fdab702c37c4bed5b59c8f |