Bile acid-induced arrhythmia is mediated by muscarinic M2 receptors in neonatal rat cardiomyocytes

Background: Intrahepatic cholestasis of pregnancy (ICP) is a common disease affecting up to 5% of pregnancies and which can cause fetal arrhythmia and sudden intrauterine death. We previously demonstrated that bile acid taurocholate (TC), which is raised in the bloodstream of ICP, can acutely alter...

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Bibliographic Details
Published in:PLoS ONE
Main Author: Sheikh Abdul Kadir S.H.; Miragoli M.; Abu-Hayyeh S.; Moshkov A.V.; Xie Q.; Keitel V.; Nikolaev V.O.; Williamson C.; Gorelik J.
Format: Article
Language:English
Published: 2010
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-77958099262&doi=10.1371%2fjournal.pone.0009689&partnerID=40&md5=068a71c7a866e3c119a66577c15c0084