Single step PCR for detection of allelic variation of MDR1 gene (P-glycoprotein) among three ethnic groups in Malaysia
Background: P-glycoprotein (PgP) is the most extensively studied ATP-binding cassette (ABC) coded by MDR1 gene. To date, 29 single nucleotide polymorphisms (SNPs) have been identified; but only SNP C3435T has been correlated with intestinal PgP expression levels and shown to influence the absorption...
Published in: | Journal of Clinical Pharmacy and Therapeutics |
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Main Author: | |
Format: | Article |
Language: | English |
Published: |
2007
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Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-34247881888&doi=10.1111%2fj.1365-2710.2007.00822.x&partnerID=40&md5=72a3352b31c2f55fc8453d234d025736 |