The relevance of CYP2D6 genetic polymorphism on chronic metoprolol therapy in cardiovascular patients

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The relevance of CYP2D6 genetic polymorphism on chronic metoprolol therapy in cardiovascular patients

Background and objective: CYP2D6 polymorphisms are well described in normal populations but there are few data on its clinical significance. We therefore investigated the influence of CYP2D6 polymorphism on steady-state plasma concentrations and apparent oral clearance of metoprolol in patients with...

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Bibliographic Details
Published in:	Journal of Clinical Pharmacy and Therapeutics
Main Author:	Ismail R.; Teh L.K.
Format:	Article
Language:	English
Published:	2006
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-33645113878&doi=10.1111%2fj.1365-2710.2006.00699.x&partnerID=40&md5=cdd9d5059ec454e0511eb80d1ea7c983

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