The relevance of CYP2D6 genetic polymorphism on chronic metoprolol therapy in cardiovascular patients

Background and objective: CYP2D6 polymorphisms are well described in normal populations but there are few data on its clinical significance. We therefore investigated the influence of CYP2D6 polymorphism on steady-state plasma concentrations and apparent oral clearance of metoprolol in patients with...

Full description

Bibliographic Details
Published in:Journal of Clinical Pharmacy and Therapeutics
Main Author: Ismail R.; Teh L.K.
Format: Article
Language:English
Published: 2006
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-33645113878&doi=10.1111%2fj.1365-2710.2006.00699.x&partnerID=40&md5=cdd9d5059ec454e0511eb80d1ea7c983