The relevance of CYP2D6 genetic polymorphism on chronic metoprolol therapy in cardiovascular patients
Background and objective: CYP2D6 polymorphisms are well described in normal populations but there are few data on its clinical significance. We therefore investigated the influence of CYP2D6 polymorphism on steady-state plasma concentrations and apparent oral clearance of metoprolol in patients with...
Published in: | Journal of Clinical Pharmacy and Therapeutics |
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Main Author: | |
Format: | Article |
Language: | English |
Published: |
2006
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Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-33645113878&doi=10.1111%2fj.1365-2710.2006.00699.x&partnerID=40&md5=cdd9d5059ec454e0511eb80d1ea7c983 |