Sperm morphology assessment in the era of intracytoplasmic sperm injection: Reliable results require focus on standardization, quality control, and training

Semen analysis is the first, and frequently, the only step in the evaluation of male fertility. Although the laboratory procedures are conducted according to the World Health Organization (WHO) guidelines, semen analysis and especially sperm morphology assessment is very difficult to standardize and...

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发表在:	World Journal of Men's Health
主要作者:	Agarwal A.; Sharma R.; Gupta S.; Finelli R.; Parekh N.; Selvam M.K.P.; Henkel R.; Durairajanayagam D.; Pompeu C.; Madani S.; Belo A.; Singh N.; Covarrubias S.; Darbandi S.; Sadeghi R.; Darbandi M.; Vogiatzi P.; Boitrelle F.; Simopoulou M.; Saleh R.; Arafa M.; Majzoub A.; Kandil H.; Zini A.; Ko E.; Alvarez J.G.; Martinez M.; Ramsay J.; Jindal S.; Busetto G.M.; Sallam H.; Maldonado I.; Anagnostopoulou C.; Alves M.G.; Sengupta P.; Gilany K.; Evenson D.P.; Lewis S.E.M.; Gosalvez J.; Ambar R.F.; Shah R.
格式:	Review
语言:	English
出版:	Korean Society for Sexual Medicine and Andrology 2021
在线阅读:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85110195134&doi=10.5534%2fWJMH.210054&partnerID=40&md5=f244cbf7a8d320931b5176f6a312a914

实物特征
总结:	Semen analysis is the first, and frequently, the only step in the evaluation of male fertility. Although the laboratory procedures are conducted according to the World Health Organization (WHO) guidelines, semen analysis and especially sperm morphology assessment is very difficult to standardize and obtain reproducible results. This is mainly due to the highly subjective nature of their evaluation. ICSI is the choice of treatment when sperm morphology is severely abnormal (teratozoospermic). Hence, the standardization of laboratory protocols for sperm morphology evaluation represents a fundamental step to ensure reliable, accurate and consistent laboratory results that avoid misdiagnoses and inadequate treatment of the infertile patient. This article aims to promote standardized laboratory procedures for an accurate evaluation of sperm morphology, including the establishment of quality control and quality assurance policies. Additionally, the clinical importance of sperm morphology results in assisted reproductive outcomes is discussed, along with the clinical management of teratozoospermic patients. © 2021 Korean Society for Sexual Medicine and Andrology. All rights reserved.
ISSN:	22874208
DOI:	10.5534/WJMH.210054

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