Novel indole based hybrid oxadiazole scaffolds with: N -(substituted-phenyl)butanamides: Synthesis, lineweaver-burk plot evaluation and binding analysis of potent urease inhibitors

In the study presented herein, 4-(1H-indol-3-yl)butanoic acid (1) was sequentially transformed in the first phase into ethyl 4-(1H-indol-3-yl)butanoate (2), 4-(1H-indol-3-yl)butanohydrazide (3) and 5-[3-(1H-indol-3-yl)propyl]-1,3,4-oxadiazole-2-thiol (4) as a nucleophile. In the second phase, variou...

全面介紹

書目詳細資料
發表在:RSC Advances
主要作者: Nazir M.; Abbasi M.A.; Aziz-Ur-Rehman; Siddiqui S.Z.; Raza H.; Hassan M.; Ali Shah S.A.; Shahid M.; Seo S.-Y.
格式: Article
語言:English
出版: Royal Society of Chemistry 2018
在線閱讀:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85050591556&doi=10.1039%2fc8ra04987d&partnerID=40&md5=fc9bed4d18b0780ebe1ed61b6140fa67