Magnesium deficiency and oxidative stress: An update

Magnesium deficiency (MgD) has been shown to impact numerous biological processes at the cellular and molecular levels. In the present review, we discuss the relationship between MgD and oxidative stress (OS). MgD is accompanied by increased levels of OS markers such as lipid, protein and DNA oxidat...

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书目详细资料
发表在:BioMedicine (Taiwan)
主要作者: 2-s2.0-84996483360
格式: Review
语言:English
出版: China Medical University 2016
在线阅读:https://www.scopus.com/inward/record.uri?eid=2-s2.0-84996483360&doi=10.7603%2fs40681-016-0020-6&partnerID=40&md5=6736074ee5b6d4d6f89fe6fbf8ac4259
实物特征
总结:Magnesium deficiency (MgD) has been shown to impact numerous biological processes at the cellular and molecular levels. In the present review, we discuss the relationship between MgD and oxidative stress (OS). MgD is accompanied by increased levels of OS markers such as lipid, protein and DNA oxidative modification products. Additionally, a relationship was detected between MgD and a weakened antioxidant defence. Different mechanisms associated with MgD are involved in the development and maintenance of OS. These mechanisms include systemic reactions such as inflammation and endothelial dysfunction, as well as changes at the cellular level, such as mitochondrial dysfunction and excessive fatty acid production. © Author(s) 2016.
ISSN:22118020
DOI:10.7603/s40681-016-0020-6