Enhancing sustained drug release property of chitosan in spheroids through crosslinking reaction and coacervation
Chitosan has not been able to be formulated as sustained-release crosslinked/coacervated drug carrier in the form of spheroids prepared by extrusion-spheronisation technique. This study re-visits chitosan spheroids and their drug (water-soluble chlorpheniramine maleate) release profiles as a functio...
出版年: | Powder Technology |
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第一著者: | |
フォーマット: | 論文 |
言語: | English |
出版事項: |
Elsevier B.V.
2019
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オンライン・アクセス: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85068459342&doi=10.1016%2fj.powtec.2019.07.006&partnerID=40&md5=e52b0510e1ba3b1ea197a265753000eb |