N-Methyl-D-Aspartate-Induced Excitotoxicity and Its Impact on the Renin-Angiotensin System in Retinal Tissue
Purpose: Renin-angiotensin system (RAS) is expressed in neuronal tissue and plays a role in neurodegenerative diseases involving excitotoxicity as a pathophysiological mechanism. In retina, excessive excitatory neurotransmission via N-methyl-d-aspartate (NMDA) receptors underlies neuronal apoptosis...
Published in: | JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS |
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Main Authors: | Irfan, Abdul Malick Sahib Mohammed; Geoffrey, Sharon; Htet, Htet; Krishnappa, Purushotham; Razali, Norhafiza; Iezhitsa, Igor; Agarwal, Renu |
Format: | Article; Early Access |
Language: | English |
Published: |
MARY ANN LIEBERT, INC
2024
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Subjects: | |
Online Access: | https://www-webofscience-com.uitm.idm.oclc.org/wos/woscc/full-recordWOS:001376688800001 |
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