New-Onset Focal to Bilateral Tonic-Clonic Seizure Following COVID-19 Vaccination
An 18-year-old male presented with new-onset focal to bilateral tonic-clonic seizures 5 days after receiving the first dose of COVID-19 vaccine. 3 days later, an identical seizure occurred lasting 1 min, leading to an acute presentation to the hospital. In hospital, the patient was loaded with intra...
Published in: | CASE REPORTS IN NEUROLOGICAL MEDICINE |
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Main Authors: | , , , |
Format: | Article |
Language: | English |
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WILEY
2024
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Online Access: | https://www-webofscience-com.uitm.idm.oclc.org/wos/woscc/full-record/WOS:001344599400001 |
author |
Phua Chun Seng; Raymond Azman Ali; Bhaskar Shalini |
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spellingShingle |
Phua Chun Seng; Raymond Azman Ali; Bhaskar Shalini New-Onset Focal to Bilateral Tonic-Clonic Seizure Following COVID-19 Vaccination Neurosciences & Neurology |
author_facet |
Phua Chun Seng; Raymond Azman Ali; Bhaskar Shalini |
author_sort |
Phua |
spelling |
Phua, Chun Seng; Raymond, Azman Ali; Bhaskar, Shalini New-Onset Focal to Bilateral Tonic-Clonic Seizure Following COVID-19 Vaccination CASE REPORTS IN NEUROLOGICAL MEDICINE English Article An 18-year-old male presented with new-onset focal to bilateral tonic-clonic seizures 5 days after receiving the first dose of COVID-19 vaccine. 3 days later, an identical seizure occurred lasting 1 min, leading to an acute presentation to the hospital. In hospital, the patient was loaded with intravenous phenytoin and started on levetiracetam with no further seizure recurrence. CT venogram and scalp EEG were unremarkable. MRI brain revealed generalised atrophy with mild bilateral hippocampal atrophy. The patient was maintained on 500 mg levetiracetam twice daily and advised to proceed with subsequent doses of vaccination. Vaccinations have been associated with breakthrough seizures. In this case, COVID-19 vaccination possibly unmasked an underlying predisposition for epilepsy. WILEY 2090-6668 2090-6676 2024 2024 10.1155/2024/8808334 Neurosciences & Neurology gold WOS:001344599400001 https://www-webofscience-com.uitm.idm.oclc.org/wos/woscc/full-record/WOS:001344599400001 |
title |
New-Onset Focal to Bilateral Tonic-Clonic Seizure Following COVID-19 Vaccination |
title_short |
New-Onset Focal to Bilateral Tonic-Clonic Seizure Following COVID-19 Vaccination |
title_full |
New-Onset Focal to Bilateral Tonic-Clonic Seizure Following COVID-19 Vaccination |
title_fullStr |
New-Onset Focal to Bilateral Tonic-Clonic Seizure Following COVID-19 Vaccination |
title_full_unstemmed |
New-Onset Focal to Bilateral Tonic-Clonic Seizure Following COVID-19 Vaccination |
title_sort |
New-Onset Focal to Bilateral Tonic-Clonic Seizure Following COVID-19 Vaccination |
container_title |
CASE REPORTS IN NEUROLOGICAL MEDICINE |
language |
English |
format |
Article |
description |
An 18-year-old male presented with new-onset focal to bilateral tonic-clonic seizures 5 days after receiving the first dose of COVID-19 vaccine. 3 days later, an identical seizure occurred lasting 1 min, leading to an acute presentation to the hospital. In hospital, the patient was loaded with intravenous phenytoin and started on levetiracetam with no further seizure recurrence. CT venogram and scalp EEG were unremarkable. MRI brain revealed generalised atrophy with mild bilateral hippocampal atrophy. The patient was maintained on 500 mg levetiracetam twice daily and advised to proceed with subsequent doses of vaccination. Vaccinations have been associated with breakthrough seizures. In this case, COVID-19 vaccination possibly unmasked an underlying predisposition for epilepsy. |
publisher |
WILEY |
issn |
2090-6668 2090-6676 |
publishDate |
2024 |
container_volume |
2024 |
container_issue |
|
doi_str_mv |
10.1155/2024/8808334 |
topic |
Neurosciences & Neurology |
topic_facet |
Neurosciences & Neurology |
accesstype |
gold |
id |
WOS:001344599400001 |
url |
https://www-webofscience-com.uitm.idm.oclc.org/wos/woscc/full-record/WOS:001344599400001 |
record_format |
wos |
collection |
Web of Science (WoS) |
_version_ |
1818940499129532416 |