Synthesis of novel indazole derivatives as inhibitors of diabetics II along with molecular docking and simulation study
In the light of the pharmacological significance of the indazole and 1, 3, 4-thiadiazole scaffold, hybrid analogs of indazole and 1, 3, 4-thiadiazole (1-14) were synthesized, identified using HREI-MS, 1H, and 13CNMR, and their capability for inhibition of alpha-amylase and alpha-glucosidase enzymes...
Published in: | JOURNAL OF MOLECULAR STRUCTURE |
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Main Authors: | Al-Nasser, Fatema; Taha, Muhammad; Rahim, Fazal; Adalat, Bushra; Chigurupati, Sridevi; Nawaz, Muhammad; Ajmal, Amar; Wadood, Abdul; Uddin, Nizam; Khan, Khalid Mohammed; Shah, Syed Adnan Ali; Felemban, Shatha Ghazi; Venugopal, Vijayan |
Format: | Article |
Language: | English |
Published: |
ELSEVIER
2025
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Subjects: | |
Online Access: | https://www-webofscience-com.uitm.idm.oclc.org/wos/woscc/full-record/WOS:001344553300001 |
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