Synthesis of novel indazole derivatives as inhibitors of diabetics II along with molecular docking and simulation study

In the light of the pharmacological significance of the indazole and 1, 3, 4-thiadiazole scaffold, hybrid analogs of indazole and 1, 3, 4-thiadiazole (1-14) were synthesized, identified using HREI-MS, 1H, and 13CNMR, and their capability for inhibition of alpha-amylase and alpha-glucosidase enzymes...

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Published in:JOURNAL OF MOLECULAR STRUCTURE
Main Authors: Al-Nasser, Fatema; Taha, Muhammad; Rahim, Fazal; Adalat, Bushra; Chigurupati, Sridevi; Nawaz, Muhammad; Ajmal, Amar; Wadood, Abdul; Uddin, Nizam; Khan, Khalid Mohammed; Shah, Syed Adnan Ali; Felemban, Shatha Ghazi; Venugopal, Vijayan
Format: Article
Language:English
Published: ELSEVIER 2025
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Online Access:https://www-webofscience-com.uitm.idm.oclc.org/wos/woscc/full-record/WOS:001344553300001