Synthesis of Novel Soritin Sulfonamide Derivatives as Potential α-Glucosidase Inhibitor and Their Molecular Docking Studies

QR Code

Synthesis of Novel Soritin Sulfonamide Derivatives as Potential α-Glucosidase Inhibitor and Their Molecular Docking Studies

Diabetes Mellitus (DM) is linked to various factors causing cardiovascular diseases, with uncontrolled postprandial hyperglycemia being a direct contributor. alpha-Glucosidase inhibitors (AGIs) aid in reducing postprandial hyperglycemia, potentially mitigating cardiovascular risks. In order to synth...

Full description

Bibliographic Details
Published in:	CHEMICAL BIOLOGY & DRUG DESIGN
Main Authors:	Inayatsyah, Nurul Alam; Ridhwan, Mohamad Jemain Mohamad; Aznirulhisham, Alim Alsukor; Rasol, Nurulfazlina Edayah; Kasim, Noraini; Imran, Syahrul
Format:	Article
Language:	English
Published:	WILEY 2024
Subjects:	Biochemistry & Molecular Biology; Pharmacology & Pharmacy
Online Access:	https://www-webofscience-com.uitm.idm.oclc.org/wos/woscc/full-record/WOS:001316873100001

Similar Items

Synthesis of Novel Soritin Sulfonamide Derivatives as Potential α-Glucosidase Inhibitor and Their Molecular Docking Studies
by: Inayatsyah N.; Ridhwan M.; Aznirulhisham A.; Rasol N.; Kasim N.; Imran S.
Published: (2024)

OPTIMIZATION OF DEPROTEINIZATION METHODS, HPLC METHOD DEVELOPMENT AND VALIDATION FOR QUANTIFICATION OF 6Β- HYDROXYTESTOSTERONE IN CELL CULTURE MEDIA
by: Ridhwan, et al.
Published: (2024)

Synthesis of Indole Based Sulfonamide Derivatives as potent inhibitors of α-glucosidase and α-amylase in management of type-II diabetes
by: Ullah W.; Rahim F.; Hayat S.; Ullah H.; Taha M.; Khan S.; Khaliq A.; Bibi S.; Gohar O.; Iqbal N.; Shah S.A.A.; Khan K.M.
Published: (2024)

Evaluation and docking of indole sulfonamide as a potent inhibitor of α-glucosidase enzyme in streptozotocin –induced diabetic albino wistar rats
by: Taha M.; Imran S.; Salahuddin M.; Iqbal N.; Rahim F.; Uddin N.; Shehzad A.; Khalid Farooq R.; Alomari M.; Mohammed Khan K.
Published: (2021)

Oxindole based oxadiazole hybrid analogs: Novel α-glucosidase inhibitors
by: Taha M.; Imran S.; Rahim F.; Wadood A.; Khan K.M.
Published: (2018)

Molecular Modeling and Synthesis of Indoline-2,3-dione-Based Benzene Sulfonamide Derivatives and Their Inhibitory Activity against α-Glucosidase and α-Amylase Enzymes
by: Rasheed L.; Rehman W.; Rahim F.; Ali Z.; Alanazi A.S.; Hussain R.; Khan I.; Alanazi M.M.; Naseer M.; Abdellattif M.H.; Hussain R.; Khan S.; Taha M.; Ali Shah S.A.
Published: (2023)

Novel quinoline derivatives as potent in vitro α-glucosidase inhibitors: In silico studies and SAR predictions
by: Taha M.; Ismail N.H.; Imran S.; Wadood A.; Rahim F.; Ali M.; Rehman A.U.
Published: (2015)

Novel thiosemicarbazide-oxadiazole hybrids as unprecedented inhibitors of yeast α-glucosidase and in silico binding analysis
by: Taha M.; Ismail N.H.; Imran S.; Wadood A.; Ali M.; Rahim F.; Khan A.A.; Riaz M.
Published: (2016)

Synthesis, α-amylase inhibition and molecular docking study of bisindolylmethane sulfonamide derivatives
by: Taha M.; Noreen T.; Imran S.; Nawaz F.; Chigurupati S.; Selvaraj M.; Rahim F.; Hadiani Ismail N.; Kumar A.; Mosaddik A.; Alghamdi A.M.; Abdulrahman nasser alqahtani Y.; Abdulrahman nasser alqahtani A.
Published: (2019)

Synthesis of novel triazinoindole-based thiourea hybrid: A study on α-glucosidase inhibitors and their molecular docking
by: Taha M.; Alshamrani F.J.; Rahim F.; Hayat S.; Ullah H.; Zaman K.; Imran S.; Khan K.M.; Naz F.
Published: (2019)

Synthesis of novel flavone hydrazones: In-vitro evaluation of α-glucosidase inhibition, QSAR analysis and docking studies
by: Imran S.; Taha M.; Ismail N.H.; Kashif S.M.; Rahim F.; Jamil W.; Hariono M.; Yusuf M.; Wahab H.
Published: (2015)

Synthesis of novel inhibitors of α-glucosidase based on the benzothiazole skeleton containing benzohydrazide moiety and their molecular docking studies
by: Taha M.; Ismail N.H.; Lalani S.; Fatmi M.Q.; Atia-Tul-Wahab; Siddiqui S.; Khan K.M.; Imran S.; Choudhary M.I.
Published: (2015)

Development of a Novel CYP3A4 Classifier Model via Site of Metabolism (SOM)-based Molecular Docking, Multivariate Analysis and Molecular Dynamics of Known Substrates and Inhibitors
by: Ridhwan M.J.M.; Hashim N.A.A.; Kasim N.; Abdullah N.N.; Inayatsyah N.A.; Abid O.; Ismail N.H.; Imran S.
Published: (2024)

Synthesis of new oxadiazole derivatives as α-glucosidase inhibitors
by: Taha M.; Ismail N.H.; Imran S.; Rokei M.Q.B.; Saad S.M.; Khan K.M.
Published: (2015)

Synthesis, α-glucosidase inhibitory, cytotoxicity and docking studies of 2-aryl-7-methylbenzimidazoles
by: Taha M.; Ismail N.H.; Imran S.; Mohamad M.H.; Wadood A.; Rahim F.; Saad S.M.; Rehman A.U.; Khan K.M.
Published: (2016)

Novel acyl hydrazide derivatives of polyhydroquinoline as potent anti-diabetic and anti-glycating agents: Synthesis, in vitro α-amylase, α-glucosidase inhibition and anti-glycating activity with molecular docking insights
by: Ur Rahman S.; Alam A.; Parveen Z.; Zainab; Assad M.; Adnan Ali Shah S.; Rafiq H.; Ayaz M.; Latif A.; Naveed Umar M.; Ali M.; Ahmad M.
Published: (2024)

Phytochemical Identification from Eleusine indica Methanolic Extract through High-Performance Liquid Chromatography Tandem Mass Spectrometry Databases- driven Analysis
by: Salim, et al.
Published: (2023)

Molecular Networking and Dereplication: Facilitating Natural Product Analysis of Piper sarmentosum Leaves
by: Salmin, et al.
Published: (2023)

Dereplication of Wrightia dubia and Wrightia pubescens by UPLC- ESI- Orbitrap-MS/MS
by: Karim, et al.
Published: (2023)

Styryllactones in the leaves of Goniothalamus lanceolatus Miq., molecular networking and their anti-dengue activity In vitro and In silico
by: Abdullah, et al.
Published: (2024)

Synthesis, α-glucosidase inhibition and molecular docking study of coumarin based derivatives
by: Taha M.; Shah S.A.A.; Afifi M.; Imran S.; Sultan S.; Rahim F.; Khan K.M.
Published: (2018)

Essential Oil Composition of Leaves from Syzygium claviflorum
by: Ab Ghani, et al.
Published: (2024)

Synthesis, in vitro and Docking Studies of New Flavone Ethers as α-Glucosidase Inhibitors
by: Imran S.; Taha M.; Ismail N.H.; Kashif S.M.; Rahim F.; Jamil W.; Wahab H.; Khan K.M.
Published: (2016)

Isolation of Phenolic Compounds from the Stem Bark of Anisoptera laevis (Dipterocarpaceae)
by: Adnan, et al.
Published: (2023)

Synthesis, in vitro α-glucosidase inhibitory potential and molecular docking study of thiadiazole analogs
by: Javid M.T.; Rahim F.; Taha M.; Rehman H.U.; Nawaz M.; wadood A.; Imran S.; Uddin I.; Mosaddik A.; Khan K.M.
Published: (2018)

Mining Secondary Metabolites of Rennellia borneensis Baill. using SIRIUS and High-Resolution Mass Spectrometry Data
by: Rushdan, et al.
Published: (2023)

ESSENTIAL OIL COMPOSITION OF Antidesma cuspidatum AND ACETYLCHOLINESTERASE INHIBITORY ACTIVITY
by: Ab Ghani, et al.
Published: (2024)

α-Glucosidase inhibition of lactone intermediates of the iminosugar deoxynojirimycin
by: Haan Y.W.; Al-Bajalan H.M.; Sage E.E.; Elangovan D.; Yajit N.L.M.; Sarizan N.M.; Zitzmann N.; Kiappes J.L.; Hasbullah S.A.; Ismail N.H.; Mackeen M.M.
Published: (2019)

Chemical Composition and Cytotoxicity of Litsea rubicunda Essential Oil from Malaysia
by: Salleh, et al.
Published: (2023)

α-Glucosidase inhibition and docking studies of 5-deoxyflavonols and dihydroflavonols isolated from abutilon Pakistanicum
by: Hussain M.; Ahmed Z.; Khan S.N.; Shah S.A.A.; Razi R.; Imran S.; Khalid M.; Ali B.; Irshad M.B.; Nawaz F.; Chaudhry M.I.
Published: (2019)

Aryl-oxadiazole Schiff bases: Synthesis, α-glucosidase in vitro inhibitory activity and their in silico studies
by: Ullah H.; Rahim F.; Taha M.; Hussain R.; Tabassum N.; Wadood A.; Nawaz M.; Mosaddik A.; Imran S.; Wahab Z.; Miana G.A.; Kanwal; Khan K.M.
Published: (2020)

Benzimidazole derivatives as new α-glucosidase inhibitors and in silico studies
by: Zawawi N.K.N.A.; Taha M.; Ahmat N.; Wadood A.; Ismail N.H.; Rahim F.; Azam S.S.; Abdullah N.
Published: (2016)

Intermedianin, a new furofuran lignan from the leaves of Knema intermedia Warb
by: Salihu, et al.
Published: (2024)

Syntheses of new 3-thiazolyl coumarin derivatives, in vitro α-glucosidase inhibitory activity, and molecular modeling studies
by: Salar U.; Taha M.; Khan K.M.; Ismail N.H.; Imran S.; Perveen S.; Gul S.; Wadood A.
Published: (2016)

Evaluation of 2-indolcarbohydrazones as potent α-glucosidase inhibitors, in silico studies and DFT based stereochemical predictions
by: Taha M.; Ismail N.H.; Javaid K.; Imran S.; Anouar E.H.; Wadood A.; Atia-Tul-Wahab; Ali M.; Khan K.M.; Saad S.M.; Rahim F.; Choudhary M.I.
Published: (2015)

Synthesis, molecular docking studies of hybrid benzimidazole as α-glucosidase inhibitor
by: Zawawi N.K.N.A.; Taha M.; Ahmat N.; Ismail N.H.; Wadood A.; Rahim F.
Published: (2017)

Antioxidant and α-glucosidase inhibitory constituents from Hornstedtia species of Malaysia
by: Hashim S.E.; Sirat H.M.; Yen K.H.; Ismail I.S.; Matsuki S.N.
Published: (2015)

Synthesis of Bis-indolylmethane sulfonohydrazides derivatives as potent α-Glucosidase inhibitors
by: Gollapalli M.; Taha M.; Ullah H.; Nawaz M.; AlMuqarrabun L.M.R.; Rahim F.; Qureshi F.; Mosaddik A.; Ahmat N.; Khan K.M.
Published: (2018)

Synthesis of piperazine sulfonamide analogs as diabetic-II inhibitors and their molecular docking study
by: Taha M.; Irshad M.; Imran S.; Chigurupati S.; Selvaraj M.; Rahim F.; Ismail N.H.; Nawaz F.; Khan K.M.
Published: (2017)

Biscoumarin analogs: Synthesis, α-glucosidase inhibitory potential and molecular docking study
by: Ahmat N.; Nik Abdullah Zawawi N.K.; Taha M.; Wadood A.; Rahim F.; Ullah H.
Published: (2020)