Assessing lifetime occupational chrysotile inhalation exposure, respiratory symptoms, and lung cancer risk among brake maintenance workers in Malaysia

This study aimed to estimate workers' occupational lifetime exposure to chrysotile and examine the respiratory symptoms and lung cancer risk. A total of 112 workers were interviewed about their occupational histories. Exposure modeling using information on the determinants of exposure was used...

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Published in:TOXICOLOGY AND INDUSTRIAL HEALTH
Main Authors: Yusof, Muhammad Zubir; Zahaba, Maryam; Mohd Aris, Mohd Shukri; Shafiee, Saiful 'Arifin; Abdul Hadi, Hazrin; Maghpor, Mohd Norhafsam; Noraini, Nor Mohd Razif
Format: Article; Early Access
Language:English
Published: SAGE PUBLICATIONS INC 2024
Subjects:
Online Access:https://www-webofscience-com.uitm.idm.oclc.org/wos/woscc/full-record/WOS:001294644200001
author Yusof
Muhammad Zubir; Zahaba
Maryam; Mohd Aris
Mohd Shukri; Shafiee
Saiful 'Arifin; Abdul Hadi
Hazrin; Maghpor
Mohd Norhafsam; Noraini
Nor Mohd Razif
spellingShingle Yusof
Muhammad Zubir; Zahaba
Maryam; Mohd Aris
Mohd Shukri; Shafiee
Saiful 'Arifin; Abdul Hadi
Hazrin; Maghpor
Mohd Norhafsam; Noraini
Nor Mohd Razif
Assessing lifetime occupational chrysotile inhalation exposure, respiratory symptoms, and lung cancer risk among brake maintenance workers in Malaysia
Public, Environmental & Occupational Health; Toxicology
author_facet Yusof
Muhammad Zubir; Zahaba
Maryam; Mohd Aris
Mohd Shukri; Shafiee
Saiful 'Arifin; Abdul Hadi
Hazrin; Maghpor
Mohd Norhafsam; Noraini
Nor Mohd Razif
author_sort Yusof
spelling Yusof, Muhammad Zubir; Zahaba, Maryam; Mohd Aris, Mohd Shukri; Shafiee, Saiful 'Arifin; Abdul Hadi, Hazrin; Maghpor, Mohd Norhafsam; Noraini, Nor Mohd Razif
Assessing lifetime occupational chrysotile inhalation exposure, respiratory symptoms, and lung cancer risk among brake maintenance workers in Malaysia
TOXICOLOGY AND INDUSTRIAL HEALTH
English
Article; Early Access
This study aimed to estimate workers' occupational lifetime exposure to chrysotile and examine the respiratory symptoms and lung cancer risk. A total of 112 workers were interviewed about their occupational histories. Exposure modeling using information on the determinants of exposure was used to estimate chrysotile emissions. The cumulative lifetime exposure was then assessed for each worker. Respiratory symptoms were obtained using a validated questionnaire. Lung cancer mortality rate was also predicted using a model. Almost all the workers were male and young (mean age = 30 years, SD = 7). The estimated lifetime occupational chrysotile inhalation exposure ranged from 0.0001 to 0.0486 f/mL.years (median = 0.0018 f/mL.years, IQR = 0.486). A high prevalence of cough symptom (11.7%), and low estimated cancer risk (<1%) were reported. In conclusion, the lung cancer risk among our cohort of workers was at a low level because of lower cumulative lifetime occupational chrysotile exposure.
SAGE PUBLICATIONS INC
0748-2337
1477-0393
2024


10.1177/07482337241273755
Public, Environmental & Occupational Health; Toxicology

WOS:001294644200001
https://www-webofscience-com.uitm.idm.oclc.org/wos/woscc/full-record/WOS:001294644200001
title Assessing lifetime occupational chrysotile inhalation exposure, respiratory symptoms, and lung cancer risk among brake maintenance workers in Malaysia
title_short Assessing lifetime occupational chrysotile inhalation exposure, respiratory symptoms, and lung cancer risk among brake maintenance workers in Malaysia
title_full Assessing lifetime occupational chrysotile inhalation exposure, respiratory symptoms, and lung cancer risk among brake maintenance workers in Malaysia
title_fullStr Assessing lifetime occupational chrysotile inhalation exposure, respiratory symptoms, and lung cancer risk among brake maintenance workers in Malaysia
title_full_unstemmed Assessing lifetime occupational chrysotile inhalation exposure, respiratory symptoms, and lung cancer risk among brake maintenance workers in Malaysia
title_sort Assessing lifetime occupational chrysotile inhalation exposure, respiratory symptoms, and lung cancer risk among brake maintenance workers in Malaysia
container_title TOXICOLOGY AND INDUSTRIAL HEALTH
language English
format Article; Early Access
description This study aimed to estimate workers' occupational lifetime exposure to chrysotile and examine the respiratory symptoms and lung cancer risk. A total of 112 workers were interviewed about their occupational histories. Exposure modeling using information on the determinants of exposure was used to estimate chrysotile emissions. The cumulative lifetime exposure was then assessed for each worker. Respiratory symptoms were obtained using a validated questionnaire. Lung cancer mortality rate was also predicted using a model. Almost all the workers were male and young (mean age = 30 years, SD = 7). The estimated lifetime occupational chrysotile inhalation exposure ranged from 0.0001 to 0.0486 f/mL.years (median = 0.0018 f/mL.years, IQR = 0.486). A high prevalence of cough symptom (11.7%), and low estimated cancer risk (<1%) were reported. In conclusion, the lung cancer risk among our cohort of workers was at a low level because of lower cumulative lifetime occupational chrysotile exposure.
publisher SAGE PUBLICATIONS INC
issn 0748-2337
1477-0393
publishDate 2024
container_volume
container_issue
doi_str_mv 10.1177/07482337241273755
topic Public, Environmental & Occupational Health; Toxicology
topic_facet Public, Environmental & Occupational Health; Toxicology
accesstype
id WOS:001294644200001
url https://www-webofscience-com.uitm.idm.oclc.org/wos/woscc/full-record/WOS:001294644200001
record_format wos
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