Cervical cancer in Malaysia

Cervical cancer is preventable due to effective screening to detect pre-malignant lesion, and vaccination against its causative organism namely human papillomavirus (HPV). This review article described current situation of cervical cancer in Malaysia. There is decreasing cervical cancer incidence in...

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Published in:JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH
Main Authors: Noor Mohamad, Noor Azura; Omar, Jamil
Format: Article; Early Access
Language:English
Published: WILEY 2024
Subjects:
Online Access:https://www-webofscience-com.uitm.idm.oclc.org/wos/woscc/full-record/WOS:001271534300001
author Noor Mohamad
Noor Azura; Omar
Jamil
spellingShingle Noor Mohamad
Noor Azura; Omar
Jamil
Cervical cancer in Malaysia
Obstetrics & Gynecology
author_facet Noor Mohamad
Noor Azura; Omar
Jamil
author_sort Noor Mohamad
spelling Noor Mohamad, Noor Azura; Omar, Jamil
Cervical cancer in Malaysia
JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH
English
Article; Early Access
Cervical cancer is preventable due to effective screening to detect pre-malignant lesion, and vaccination against its causative organism namely human papillomavirus (HPV). This review article described current situation of cervical cancer in Malaysia. There is decreasing cervical cancer incidence in the country, with age-standardized rate of 10.3, versus 14.1 and 7.5 per 100 000 for worldwide and high-income countries, respectively. School-based HPV vaccination is part of national immunization since 2010, with yearly coverage rate of 83%-91%. The figure declined during coronavirus disease-19 pandemic due to scarce vaccine supply and movement-control order, resulting in about 500 000 students missing their course, with catch-up program currently onboard. Opportunistic cervical screening program started in 1960s with cervical smear cytology, which is succeeded by HPV DNA screening since 2020. Cervical cytology remains indispensable screening method in healthcare facility without access to HPV test kit, and used to triage high-risk HPV positive with abnormal cytology that require urgent colposcopy. Computed tomography is the main imaging modality to assess local and distal extent of cervical cancer. Primary surgical treatment for early-stage cancer is performed by trained gynecologic oncologist, with long waiting list for radiation therapy in locally advanced disease due to limited available public facility. There is restricted access to targeted therapy due to high treatment cost. In conclusion, Malaysia is heading toward cervical cancer elimination through rigorous investment in primary and secondary prevention, and increase in public engagement with the support of government policy enforcement.
WILEY
1341-8076
1447-0756
2024


10.1111/jog.16031
Obstetrics & Gynecology

WOS:001271534300001
https://www-webofscience-com.uitm.idm.oclc.org/wos/woscc/full-record/WOS:001271534300001
title Cervical cancer in Malaysia
title_short Cervical cancer in Malaysia
title_full Cervical cancer in Malaysia
title_fullStr Cervical cancer in Malaysia
title_full_unstemmed Cervical cancer in Malaysia
title_sort Cervical cancer in Malaysia
container_title JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH
language English
format Article; Early Access
description Cervical cancer is preventable due to effective screening to detect pre-malignant lesion, and vaccination against its causative organism namely human papillomavirus (HPV). This review article described current situation of cervical cancer in Malaysia. There is decreasing cervical cancer incidence in the country, with age-standardized rate of 10.3, versus 14.1 and 7.5 per 100 000 for worldwide and high-income countries, respectively. School-based HPV vaccination is part of national immunization since 2010, with yearly coverage rate of 83%-91%. The figure declined during coronavirus disease-19 pandemic due to scarce vaccine supply and movement-control order, resulting in about 500 000 students missing their course, with catch-up program currently onboard. Opportunistic cervical screening program started in 1960s with cervical smear cytology, which is succeeded by HPV DNA screening since 2020. Cervical cytology remains indispensable screening method in healthcare facility without access to HPV test kit, and used to triage high-risk HPV positive with abnormal cytology that require urgent colposcopy. Computed tomography is the main imaging modality to assess local and distal extent of cervical cancer. Primary surgical treatment for early-stage cancer is performed by trained gynecologic oncologist, with long waiting list for radiation therapy in locally advanced disease due to limited available public facility. There is restricted access to targeted therapy due to high treatment cost. In conclusion, Malaysia is heading toward cervical cancer elimination through rigorous investment in primary and secondary prevention, and increase in public engagement with the support of government policy enforcement.
publisher WILEY
issn 1341-8076
1447-0756
publishDate 2024
container_volume
container_issue
doi_str_mv 10.1111/jog.16031
topic Obstetrics & Gynecology
topic_facet Obstetrics & Gynecology
accesstype
id WOS:001271534300001
url https://www-webofscience-com.uitm.idm.oclc.org/wos/woscc/full-record/WOS:001271534300001
record_format wos
collection Web of Science (WoS)
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