Iron-related Genes and Proteins Involved in Iron Homeostasis in Animal Models of Allergic Asthma: A Systematic Review

The involvement of the immune oxidative stress response in the pathophysiology and pathogenesis of allergic asthma is well documented. However, reports on the role of iron homeostasis in allergic asthma is scarce. Therefore, this study aims to identify iron-related genes and proteins in mouse models...

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Published in:BIOLOGICAL TRACE ELEMENT RESEARCH
Main Authors: Wafriy, Che Ismail; Nor-Ashikin, Mohamed Noor Khan; Kamsani, Yuhaniza Shafinie; Muid, Suhaila Abd; Sarbandi, Mimi Sophia
Format: Review; Early Access
Language:English
Published: SPRINGERNATURE 2024
Subjects:
Online Access:https://www-webofscience-com.uitm.idm.oclc.org/wos/woscc/full-record/WOS:001216076300002
author Wafriy
Che Ismail; Nor-Ashikin
Mohamed Noor Khan; Kamsani
Yuhaniza Shafinie; Muid
Suhaila Abd; Sarbandi
Mimi Sophia
spellingShingle Wafriy
Che Ismail; Nor-Ashikin
Mohamed Noor Khan; Kamsani
Yuhaniza Shafinie; Muid
Suhaila Abd; Sarbandi
Mimi Sophia
Iron-related Genes and Proteins Involved in Iron Homeostasis in Animal Models of Allergic Asthma: A Systematic Review
Biochemistry & Molecular Biology; Endocrinology & Metabolism
author_facet Wafriy
Che Ismail; Nor-Ashikin
Mohamed Noor Khan; Kamsani
Yuhaniza Shafinie; Muid
Suhaila Abd; Sarbandi
Mimi Sophia
author_sort Wafriy
spelling Wafriy, Che Ismail; Nor-Ashikin, Mohamed Noor Khan; Kamsani, Yuhaniza Shafinie; Muid, Suhaila Abd; Sarbandi, Mimi Sophia
Iron-related Genes and Proteins Involved in Iron Homeostasis in Animal Models of Allergic Asthma: A Systematic Review
BIOLOGICAL TRACE ELEMENT RESEARCH
English
Review; Early Access
The involvement of the immune oxidative stress response in the pathophysiology and pathogenesis of allergic asthma is well documented. However, reports on the role of iron homeostasis in allergic asthma is scarce. Therefore, this study aims to identify iron-related genes and proteins in mouse models of allergic asthma. Related articles were identified from SCOPUS and Web of Science databases. The article search was limited to publications in English, within a 10-year period (2014 - 2023, up to 16 August 2023) and original/research papers. All identified articles were screened for eligibility using the inclusion and exclusion criteria. All eligible articles were quality appraised prior to data extraction. Five studies were selected for data extraction. Based on the extracted data, three themes and seven subthemes related to iron homeostasis were identified. The type of samples and analytical methods used were also identified. In conclusion, our study elucidates that iron-related proteins are regulated in animal models of allergic asthma. However, the currently available data do not allow us to conclude whether the disease model resulted in iron accumulation or depletion. Therefore, further studies with other related markers should be conducted.
SPRINGERNATURE
0163-4984
1559-0720
2024


10.1007/s12011-024-04183-8
Biochemistry & Molecular Biology; Endocrinology & Metabolism

WOS:001216076300002
https://www-webofscience-com.uitm.idm.oclc.org/wos/woscc/full-record/WOS:001216076300002
title Iron-related Genes and Proteins Involved in Iron Homeostasis in Animal Models of Allergic Asthma: A Systematic Review
title_short Iron-related Genes and Proteins Involved in Iron Homeostasis in Animal Models of Allergic Asthma: A Systematic Review
title_full Iron-related Genes and Proteins Involved in Iron Homeostasis in Animal Models of Allergic Asthma: A Systematic Review
title_fullStr Iron-related Genes and Proteins Involved in Iron Homeostasis in Animal Models of Allergic Asthma: A Systematic Review
title_full_unstemmed Iron-related Genes and Proteins Involved in Iron Homeostasis in Animal Models of Allergic Asthma: A Systematic Review
title_sort Iron-related Genes and Proteins Involved in Iron Homeostasis in Animal Models of Allergic Asthma: A Systematic Review
container_title BIOLOGICAL TRACE ELEMENT RESEARCH
language English
format Review; Early Access
description The involvement of the immune oxidative stress response in the pathophysiology and pathogenesis of allergic asthma is well documented. However, reports on the role of iron homeostasis in allergic asthma is scarce. Therefore, this study aims to identify iron-related genes and proteins in mouse models of allergic asthma. Related articles were identified from SCOPUS and Web of Science databases. The article search was limited to publications in English, within a 10-year period (2014 - 2023, up to 16 August 2023) and original/research papers. All identified articles were screened for eligibility using the inclusion and exclusion criteria. All eligible articles were quality appraised prior to data extraction. Five studies were selected for data extraction. Based on the extracted data, three themes and seven subthemes related to iron homeostasis were identified. The type of samples and analytical methods used were also identified. In conclusion, our study elucidates that iron-related proteins are regulated in animal models of allergic asthma. However, the currently available data do not allow us to conclude whether the disease model resulted in iron accumulation or depletion. Therefore, further studies with other related markers should be conducted.
publisher SPRINGERNATURE
issn 0163-4984
1559-0720
publishDate 2024
container_volume
container_issue
doi_str_mv 10.1007/s12011-024-04183-8
topic Biochemistry & Molecular Biology; Endocrinology & Metabolism
topic_facet Biochemistry & Molecular Biology; Endocrinology & Metabolism
accesstype
id WOS:001216076300002
url https://www-webofscience-com.uitm.idm.oclc.org/wos/woscc/full-record/WOS:001216076300002
record_format wos
collection Web of Science (WoS)
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