Exploring the synthesis, molecular structure and biological activities of novel Bis-Schiff base derivatives: A combined theoretical and experimental approach

A library of six novel bis-Schiff base derivatives (2a -f) were synthesized, characterized through modern spectroscopic techniques and screened for their alpha-glucosidase and alpha-amylase inhibitory activities (in vitro). In the series, compound 2a (IC50 = 5.64 +/- 2.22 mu M) and 2f (IC50 = 22.78...

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Published in:JOURNAL OF MOLECULAR STRUCTURE
Main Authors: Gul, Sana; Alam, Aftab; Zainab; Mohammad, Assad; Elhenawy, Ahmed A.; Islam, Mohammad Shahidul; Shah, Syed Adnan Ali; Parveen, Zahida; Shah, Tanzeela Ahmad; Ahmad, Manzoor
Format: Article
Language:English
Published: ELSEVIER 2024
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Online Access:https://www-webofscience-com.uitm.idm.oclc.org/wos/woscc/full-record/WOS:001207472700001